Laser-Degeneration Study of Nerve Fibers in the Optic Nerve

Autores
Carri, Néstor; Campaña, Hebe Edith; Suburo, Ángela; Duchowicz, Ricardo; Gallardo, Mario; Garavaglia, Mario J.
Año de publicación
1980
Idioma
inglés
Tipo de recurso
artículo
Estado
versión enviada
Descripción
Knowledge about wiring of neurons is one of the most important goals of neurobiology. Neuronal processes -axons and dendrites- degenerate when they are severed from their cell body. Since different staining procedures distinguish between the degenerating axons and their healthy neighbors, most neuroanatomical pathways have been mapped through the follow-up of degenerating axons after spontaneous or experimental lesions at some point of the pathway. Mapping of neuroanatomical connections has been enormously enriched during the past few years, thanks to new labelling techniques with great resolution power [1]. However, the resolution of the older degeneration procedures is only limited by the extent of the lesion and the resolution of the differential staining of degenerating axons. As we will show in this report, the use of a laser to produce small lesions in the retina of birds, coupled to the detection of degenerating axons in semi-thin plastic sections [2] is allowing us to understand the relationship between axons along the optic pathway with a resolution comparable to that of “in vivo” labelling techniques.
Materia
Óptica, Acústica
degenerating axons
wiring of neuron
detection of degenerating axons
laser
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nd/4.0/
Repositorio
CIC Digital (CICBA)
Institución
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
OAI Identificador
oai:digital.cic.gba.gob.ar:11746/1936

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network_acronym_str CICBA
repository_id_str 9441
network_name_str CIC Digital (CICBA)
spelling Laser-Degeneration Study of Nerve Fibers in the Optic NerveCarri, NéstorCampaña, Hebe EdithSuburo, ÁngelaDuchowicz, RicardoGallardo, MarioGaravaglia, Mario J.Óptica, Acústicadegenerating axonswiring of neurondetection of degenerating axonslaserKnowledge about wiring of neurons is one of the most important goals of neurobiology. Neuronal processes -axons and dendrites- degenerate when they are severed from their cell body. Since different staining procedures distinguish between the degenerating axons and their healthy neighbors, most neuroanatomical pathways have been mapped through the follow-up of degenerating axons after spontaneous or experimental lesions at some point of the pathway. Mapping of neuroanatomical connections has been enormously enriched during the past few years, thanks to new labelling techniques with great resolution power [1]. However, the resolution of the older degeneration procedures is only limited by the extent of the lesion and the resolution of the differential staining of degenerating axons. As we will show in this report, the use of a laser to produce small lesions in the retina of birds, coupled to the detection of degenerating axons in semi-thin plastic sections [2] is allowing us to understand the relationship between axons along the optic pathway with a resolution comparable to that of “in vivo” labelling techniques.1980-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/submittedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://digital.cic.gba.gob.ar/handle/11746/1936enginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nd/4.0/reponame:CIC Digital (CICBA)instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Airesinstacron:CICBA2025-09-29T13:40:00Zoai:digital.cic.gba.gob.ar:11746/1936Institucionalhttp://digital.cic.gba.gob.arOrganismo científico-tecnológicoNo correspondehttp://digital.cic.gba.gob.ar/oai/snrdmarisa.degiusti@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:94412025-09-29 13:40:00.747CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Airesfalse
dc.title.none.fl_str_mv Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
title Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
spellingShingle Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
Carri, Néstor
Óptica, Acústica
degenerating axons
wiring of neuron
detection of degenerating axons
laser
title_short Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
title_full Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
title_fullStr Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
title_full_unstemmed Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
title_sort Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
dc.creator.none.fl_str_mv Carri, Néstor
Campaña, Hebe Edith
Suburo, Ángela
Duchowicz, Ricardo
Gallardo, Mario
Garavaglia, Mario J.
author Carri, Néstor
author_facet Carri, Néstor
Campaña, Hebe Edith
Suburo, Ángela
Duchowicz, Ricardo
Gallardo, Mario
Garavaglia, Mario J.
author_role author
author2 Campaña, Hebe Edith
Suburo, Ángela
Duchowicz, Ricardo
Gallardo, Mario
Garavaglia, Mario J.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Óptica, Acústica
degenerating axons
wiring of neuron
detection of degenerating axons
laser
topic Óptica, Acústica
degenerating axons
wiring of neuron
detection of degenerating axons
laser
dc.description.none.fl_txt_mv Knowledge about wiring of neurons is one of the most important goals of neurobiology. Neuronal processes -axons and dendrites- degenerate when they are severed from their cell body. Since different staining procedures distinguish between the degenerating axons and their healthy neighbors, most neuroanatomical pathways have been mapped through the follow-up of degenerating axons after spontaneous or experimental lesions at some point of the pathway. Mapping of neuroanatomical connections has been enormously enriched during the past few years, thanks to new labelling techniques with great resolution power [1]. However, the resolution of the older degeneration procedures is only limited by the extent of the lesion and the resolution of the differential staining of degenerating axons. As we will show in this report, the use of a laser to produce small lesions in the retina of birds, coupled to the detection of degenerating axons in semi-thin plastic sections [2] is allowing us to understand the relationship between axons along the optic pathway with a resolution comparable to that of “in vivo” labelling techniques.
description Knowledge about wiring of neurons is one of the most important goals of neurobiology. Neuronal processes -axons and dendrites- degenerate when they are severed from their cell body. Since different staining procedures distinguish between the degenerating axons and their healthy neighbors, most neuroanatomical pathways have been mapped through the follow-up of degenerating axons after spontaneous or experimental lesions at some point of the pathway. Mapping of neuroanatomical connections has been enormously enriched during the past few years, thanks to new labelling techniques with great resolution power [1]. However, the resolution of the older degeneration procedures is only limited by the extent of the lesion and the resolution of the differential staining of degenerating axons. As we will show in this report, the use of a laser to produce small lesions in the retina of birds, coupled to the detection of degenerating axons in semi-thin plastic sections [2] is allowing us to understand the relationship between axons along the optic pathway with a resolution comparable to that of “in vivo” labelling techniques.
publishDate 1980
dc.date.none.fl_str_mv 1980-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/submittedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str submittedVersion
dc.identifier.none.fl_str_mv https://digital.cic.gba.gob.ar/handle/11746/1936
url https://digital.cic.gba.gob.ar/handle/11746/1936
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nd/4.0/
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:CIC Digital (CICBA)
instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
instacron:CICBA
reponame_str CIC Digital (CICBA)
collection CIC Digital (CICBA)
instname_str Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
instacron_str CICBA
institution CICBA
repository.name.fl_str_mv CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
repository.mail.fl_str_mv marisa.degiusti@sedici.unlp.edu.ar
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