Laser-Degeneration Study of Nerve Fibers in the Optic Nerve
- Autores
- Carri, Néstor; Campaña, Hebe Edith; Suburo, Ángela; Duchowicz, Ricardo; Gallardo, Mario; Garavaglia, Mario J.
- Año de publicación
- 1980
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión enviada
- Descripción
- Knowledge about wiring of neurons is one of the most important goals of neurobiology. Neuronal processes -axons and dendrites- degenerate when they are severed from their cell body. Since different staining procedures distinguish between the degenerating axons and their healthy neighbors, most neuroanatomical pathways have been mapped through the follow-up of degenerating axons after spontaneous or experimental lesions at some point of the pathway. Mapping of neuroanatomical connections has been enormously enriched during the past few years, thanks to new labelling techniques with great resolution power [1]. However, the resolution of the older degeneration procedures is only limited by the extent of the lesion and the resolution of the differential staining of degenerating axons. As we will show in this report, the use of a laser to produce small lesions in the retina of birds, coupled to the detection of degenerating axons in semi-thin plastic sections [2] is allowing us to understand the relationship between axons along the optic pathway with a resolution comparable to that of “in vivo” labelling techniques.
- Materia
-
Óptica, Acústica
degenerating axons
wiring of neuron
detection of degenerating axons
laser - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by-nd/4.0/
- Repositorio
- Institución
- Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
- OAI Identificador
- oai:digital.cic.gba.gob.ar:11746/1936
Ver los metadatos del registro completo
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spelling |
Laser-Degeneration Study of Nerve Fibers in the Optic NerveCarri, NéstorCampaña, Hebe EdithSuburo, ÁngelaDuchowicz, RicardoGallardo, MarioGaravaglia, Mario J.Óptica, Acústicadegenerating axonswiring of neurondetection of degenerating axonslaserKnowledge about wiring of neurons is one of the most important goals of neurobiology. Neuronal processes -axons and dendrites- degenerate when they are severed from their cell body. Since different staining procedures distinguish between the degenerating axons and their healthy neighbors, most neuroanatomical pathways have been mapped through the follow-up of degenerating axons after spontaneous or experimental lesions at some point of the pathway. Mapping of neuroanatomical connections has been enormously enriched during the past few years, thanks to new labelling techniques with great resolution power [1]. However, the resolution of the older degeneration procedures is only limited by the extent of the lesion and the resolution of the differential staining of degenerating axons. As we will show in this report, the use of a laser to produce small lesions in the retina of birds, coupled to the detection of degenerating axons in semi-thin plastic sections [2] is allowing us to understand the relationship between axons along the optic pathway with a resolution comparable to that of “in vivo” labelling techniques.1980-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/submittedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://digital.cic.gba.gob.ar/handle/11746/1936enginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nd/4.0/reponame:CIC Digital (CICBA)instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Airesinstacron:CICBA2025-09-29T13:40:00Zoai:digital.cic.gba.gob.ar:11746/1936Institucionalhttp://digital.cic.gba.gob.arOrganismo científico-tecnológicoNo correspondehttp://digital.cic.gba.gob.ar/oai/snrdmarisa.degiusti@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:94412025-09-29 13:40:00.747CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Airesfalse |
dc.title.none.fl_str_mv |
Laser-Degeneration Study of Nerve Fibers in the Optic Nerve |
title |
Laser-Degeneration Study of Nerve Fibers in the Optic Nerve |
spellingShingle |
Laser-Degeneration Study of Nerve Fibers in the Optic Nerve Carri, Néstor Óptica, Acústica degenerating axons wiring of neuron detection of degenerating axons laser |
title_short |
Laser-Degeneration Study of Nerve Fibers in the Optic Nerve |
title_full |
Laser-Degeneration Study of Nerve Fibers in the Optic Nerve |
title_fullStr |
Laser-Degeneration Study of Nerve Fibers in the Optic Nerve |
title_full_unstemmed |
Laser-Degeneration Study of Nerve Fibers in the Optic Nerve |
title_sort |
Laser-Degeneration Study of Nerve Fibers in the Optic Nerve |
dc.creator.none.fl_str_mv |
Carri, Néstor Campaña, Hebe Edith Suburo, Ángela Duchowicz, Ricardo Gallardo, Mario Garavaglia, Mario J. |
author |
Carri, Néstor |
author_facet |
Carri, Néstor Campaña, Hebe Edith Suburo, Ángela Duchowicz, Ricardo Gallardo, Mario Garavaglia, Mario J. |
author_role |
author |
author2 |
Campaña, Hebe Edith Suburo, Ángela Duchowicz, Ricardo Gallardo, Mario Garavaglia, Mario J. |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
Óptica, Acústica degenerating axons wiring of neuron detection of degenerating axons laser |
topic |
Óptica, Acústica degenerating axons wiring of neuron detection of degenerating axons laser |
dc.description.none.fl_txt_mv |
Knowledge about wiring of neurons is one of the most important goals of neurobiology. Neuronal processes -axons and dendrites- degenerate when they are severed from their cell body. Since different staining procedures distinguish between the degenerating axons and their healthy neighbors, most neuroanatomical pathways have been mapped through the follow-up of degenerating axons after spontaneous or experimental lesions at some point of the pathway. Mapping of neuroanatomical connections has been enormously enriched during the past few years, thanks to new labelling techniques with great resolution power [1]. However, the resolution of the older degeneration procedures is only limited by the extent of the lesion and the resolution of the differential staining of degenerating axons. As we will show in this report, the use of a laser to produce small lesions in the retina of birds, coupled to the detection of degenerating axons in semi-thin plastic sections [2] is allowing us to understand the relationship between axons along the optic pathway with a resolution comparable to that of “in vivo” labelling techniques. |
description |
Knowledge about wiring of neurons is one of the most important goals of neurobiology. Neuronal processes -axons and dendrites- degenerate when they are severed from their cell body. Since different staining procedures distinguish between the degenerating axons and their healthy neighbors, most neuroanatomical pathways have been mapped through the follow-up of degenerating axons after spontaneous or experimental lesions at some point of the pathway. Mapping of neuroanatomical connections has been enormously enriched during the past few years, thanks to new labelling techniques with great resolution power [1]. However, the resolution of the older degeneration procedures is only limited by the extent of the lesion and the resolution of the differential staining of degenerating axons. As we will show in this report, the use of a laser to produce small lesions in the retina of birds, coupled to the detection of degenerating axons in semi-thin plastic sections [2] is allowing us to understand the relationship between axons along the optic pathway with a resolution comparable to that of “in vivo” labelling techniques. |
publishDate |
1980 |
dc.date.none.fl_str_mv |
1980-07 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/submittedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
submittedVersion |
dc.identifier.none.fl_str_mv |
https://digital.cic.gba.gob.ar/handle/11746/1936 |
url |
https://digital.cic.gba.gob.ar/handle/11746/1936 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nd/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nd/4.0/ |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:CIC Digital (CICBA) instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires instacron:CICBA |
reponame_str |
CIC Digital (CICBA) |
collection |
CIC Digital (CICBA) |
instname_str |
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires |
instacron_str |
CICBA |
institution |
CICBA |
repository.name.fl_str_mv |
CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Aires |
repository.mail.fl_str_mv |
marisa.degiusti@sedici.unlp.edu.ar |
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1844618592816988160 |
score |
13.070432 |