Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?

Autores
Pérez-Cuesta, L.M.; Maldonado, H.
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A conditioned stimulus (CS) exposure has the ability to induce two qualitatively different mnesic processes: memory reconsolidation and memory extinction. Previous work from our laboratory has shown that upon a single CS presentation the triggering of one or the other process depends on CS duration (short CS exposure triggers reconsolidation, whereas a long CS exposure triggers extinction), both being mutually exclusive processes. Here we show that either process is triggered only after CS offset, ruling out an interaction as the mechanism of this mutual exclusion. Also, we show here for the first time that reconsolidation and extinction can occur simultaneously without interfering with each other if they are serially triggered by respective short and long CS exposures. Thus, we conclude that (1) one single CS presentation triggers one single process, after CS offset, and (2) whether memory reconsolidation and extinction mutually exclude each other or whether they coexist depends only on whether they are triggered by single or multiple CS presentations. © 2009 Cold Spring Harbor Laboratory Press.
Fil:Pérez-Cuesta, L.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
Fuente
Learn. Mem. 2009;16(11):714-721
Materia
animal experiment
article
aversion
conditioning
controlled study
crab
exposure
learning
long term memory
male
memory consolidation
nonhuman
priority journal
reinforcement
stimulus
symbiosis
training
working memory
Animals
Behavior, Animal
Brachyura
Conditioning, Classical
Cycloheximide
Extinction, Psychological
Male
Memory
Protein Synthesis Inhibitors
Time Factors
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/2.5/ar
Repositorio
Biblioteca Digital (UBA-FCEN)
Institución
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
OAI Identificador
paperaa:paper_10720502_v16_n11_p714_PerezCuesta

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oai_identifier_str paperaa:paper_10720502_v16_n11_p714_PerezCuesta
network_acronym_str BDUBAFCEN
repository_id_str 1896
network_name_str Biblioteca Digital (UBA-FCEN)
spelling Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?Pérez-Cuesta, L.M.Maldonado, H.animal experimentarticleaversionconditioningcontrolled studycrabexposurelearninglong term memorymalememory consolidationnonhumanpriority journalreinforcementstimulussymbiosistrainingworking memoryAnimalsBehavior, AnimalBrachyuraConditioning, ClassicalCycloheximideExtinction, PsychologicalMaleMemoryProtein Synthesis InhibitorsTime FactorsA conditioned stimulus (CS) exposure has the ability to induce two qualitatively different mnesic processes: memory reconsolidation and memory extinction. Previous work from our laboratory has shown that upon a single CS presentation the triggering of one or the other process depends on CS duration (short CS exposure triggers reconsolidation, whereas a long CS exposure triggers extinction), both being mutually exclusive processes. Here we show that either process is triggered only after CS offset, ruling out an interaction as the mechanism of this mutual exclusion. Also, we show here for the first time that reconsolidation and extinction can occur simultaneously without interfering with each other if they are serially triggered by respective short and long CS exposures. Thus, we conclude that (1) one single CS presentation triggers one single process, after CS offset, and (2) whether memory reconsolidation and extinction mutually exclude each other or whether they coexist depends only on whether they are triggered by single or multiple CS presentations. © 2009 Cold Spring Harbor Laboratory Press.Fil:Pérez-Cuesta, L.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.2009info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12110/paper_10720502_v16_n11_p714_PerezCuestaLearn. Mem. 2009;16(11):714-721reponame:Biblioteca Digital (UBA-FCEN)instname:Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturalesinstacron:UBA-FCENenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/ar2025-10-23T11:18:30Zpaperaa:paper_10720502_v16_n11_p714_PerezCuestaInstitucionalhttps://digital.bl.fcen.uba.ar/Universidad públicaNo correspondehttps://digital.bl.fcen.uba.ar/cgi-bin/oaiserver.cgiana@bl.fcen.uba.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:18962025-10-23 11:18:32.714Biblioteca Digital (UBA-FCEN) - Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturalesfalse
dc.title.none.fl_str_mv Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
title Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
spellingShingle Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
Pérez-Cuesta, L.M.
animal experiment
article
aversion
conditioning
controlled study
crab
exposure
learning
long term memory
male
memory consolidation
nonhuman
priority journal
reinforcement
stimulus
symbiosis
training
working memory
Animals
Behavior, Animal
Brachyura
Conditioning, Classical
Cycloheximide
Extinction, Psychological
Male
Memory
Protein Synthesis Inhibitors
Time Factors
title_short Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
title_full Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
title_fullStr Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
title_full_unstemmed Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
title_sort Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
dc.creator.none.fl_str_mv Pérez-Cuesta, L.M.
Maldonado, H.
author Pérez-Cuesta, L.M.
author_facet Pérez-Cuesta, L.M.
Maldonado, H.
author_role author
author2 Maldonado, H.
author2_role author
dc.subject.none.fl_str_mv animal experiment
article
aversion
conditioning
controlled study
crab
exposure
learning
long term memory
male
memory consolidation
nonhuman
priority journal
reinforcement
stimulus
symbiosis
training
working memory
Animals
Behavior, Animal
Brachyura
Conditioning, Classical
Cycloheximide
Extinction, Psychological
Male
Memory
Protein Synthesis Inhibitors
Time Factors
topic animal experiment
article
aversion
conditioning
controlled study
crab
exposure
learning
long term memory
male
memory consolidation
nonhuman
priority journal
reinforcement
stimulus
symbiosis
training
working memory
Animals
Behavior, Animal
Brachyura
Conditioning, Classical
Cycloheximide
Extinction, Psychological
Male
Memory
Protein Synthesis Inhibitors
Time Factors
dc.description.none.fl_txt_mv A conditioned stimulus (CS) exposure has the ability to induce two qualitatively different mnesic processes: memory reconsolidation and memory extinction. Previous work from our laboratory has shown that upon a single CS presentation the triggering of one or the other process depends on CS duration (short CS exposure triggers reconsolidation, whereas a long CS exposure triggers extinction), both being mutually exclusive processes. Here we show that either process is triggered only after CS offset, ruling out an interaction as the mechanism of this mutual exclusion. Also, we show here for the first time that reconsolidation and extinction can occur simultaneously without interfering with each other if they are serially triggered by respective short and long CS exposures. Thus, we conclude that (1) one single CS presentation triggers one single process, after CS offset, and (2) whether memory reconsolidation and extinction mutually exclude each other or whether they coexist depends only on whether they are triggered by single or multiple CS presentations. © 2009 Cold Spring Harbor Laboratory Press.
Fil:Pérez-Cuesta, L.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
description A conditioned stimulus (CS) exposure has the ability to induce two qualitatively different mnesic processes: memory reconsolidation and memory extinction. Previous work from our laboratory has shown that upon a single CS presentation the triggering of one or the other process depends on CS duration (short CS exposure triggers reconsolidation, whereas a long CS exposure triggers extinction), both being mutually exclusive processes. Here we show that either process is triggered only after CS offset, ruling out an interaction as the mechanism of this mutual exclusion. Also, we show here for the first time that reconsolidation and extinction can occur simultaneously without interfering with each other if they are serially triggered by respective short and long CS exposures. Thus, we conclude that (1) one single CS presentation triggers one single process, after CS offset, and (2) whether memory reconsolidation and extinction mutually exclude each other or whether they coexist depends only on whether they are triggered by single or multiple CS presentations. © 2009 Cold Spring Harbor Laboratory Press.
publishDate 2009
dc.date.none.fl_str_mv 2009
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12110/paper_10720502_v16_n11_p714_PerezCuesta
url http://hdl.handle.net/20.500.12110/paper_10720502_v16_n11_p714_PerezCuesta
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/2.5/ar
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/2.5/ar
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Learn. Mem. 2009;16(11):714-721
reponame:Biblioteca Digital (UBA-FCEN)
instname:Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
reponame_str Biblioteca Digital (UBA-FCEN)
collection Biblioteca Digital (UBA-FCEN)
instname_str Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron_str UBA-FCEN
institution UBA-FCEN
repository.name.fl_str_mv Biblioteca Digital (UBA-FCEN) - Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
repository.mail.fl_str_mv ana@bl.fcen.uba.ar
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