Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?
- Autores
- Pérez-Cuesta, L.M.; Maldonado, H.
- Año de publicación
- 2009
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- A conditioned stimulus (CS) exposure has the ability to induce two qualitatively different mnesic processes: memory reconsolidation and memory extinction. Previous work from our laboratory has shown that upon a single CS presentation the triggering of one or the other process depends on CS duration (short CS exposure triggers reconsolidation, whereas a long CS exposure triggers extinction), both being mutually exclusive processes. Here we show that either process is triggered only after CS offset, ruling out an interaction as the mechanism of this mutual exclusion. Also, we show here for the first time that reconsolidation and extinction can occur simultaneously without interfering with each other if they are serially triggered by respective short and long CS exposures. Thus, we conclude that (1) one single CS presentation triggers one single process, after CS offset, and (2) whether memory reconsolidation and extinction mutually exclude each other or whether they coexist depends only on whether they are triggered by single or multiple CS presentations. © 2009 Cold Spring Harbor Laboratory Press.
Fil:Pérez-Cuesta, L.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. - Fuente
- Learn. Mem. 2009;16(11):714-721
- Materia
-
animal experiment
article
aversion
conditioning
controlled study
crab
exposure
learning
long term memory
male
memory consolidation
nonhuman
priority journal
reinforcement
stimulus
symbiosis
training
working memory
Animals
Behavior, Animal
Brachyura
Conditioning, Classical
Cycloheximide
Extinction, Psychological
Male
Memory
Protein Synthesis Inhibitors
Time Factors - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by/2.5/ar
- Repositorio
- Institución
- Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
- OAI Identificador
- paperaa:paper_10720502_v16_n11_p714_PerezCuesta
Ver los metadatos del registro completo
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Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence?Pérez-Cuesta, L.M.Maldonado, H.animal experimentarticleaversionconditioningcontrolled studycrabexposurelearninglong term memorymalememory consolidationnonhumanpriority journalreinforcementstimulussymbiosistrainingworking memoryAnimalsBehavior, AnimalBrachyuraConditioning, ClassicalCycloheximideExtinction, PsychologicalMaleMemoryProtein Synthesis InhibitorsTime FactorsA conditioned stimulus (CS) exposure has the ability to induce two qualitatively different mnesic processes: memory reconsolidation and memory extinction. Previous work from our laboratory has shown that upon a single CS presentation the triggering of one or the other process depends on CS duration (short CS exposure triggers reconsolidation, whereas a long CS exposure triggers extinction), both being mutually exclusive processes. Here we show that either process is triggered only after CS offset, ruling out an interaction as the mechanism of this mutual exclusion. Also, we show here for the first time that reconsolidation and extinction can occur simultaneously without interfering with each other if they are serially triggered by respective short and long CS exposures. Thus, we conclude that (1) one single CS presentation triggers one single process, after CS offset, and (2) whether memory reconsolidation and extinction mutually exclude each other or whether they coexist depends only on whether they are triggered by single or multiple CS presentations. © 2009 Cold Spring Harbor Laboratory Press.Fil:Pérez-Cuesta, L.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.2009info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12110/paper_10720502_v16_n11_p714_PerezCuestaLearn. Mem. 2009;16(11):714-721reponame:Biblioteca Digital (UBA-FCEN)instname:Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturalesinstacron:UBA-FCENenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/ar2025-10-23T11:18:30Zpaperaa:paper_10720502_v16_n11_p714_PerezCuestaInstitucionalhttps://digital.bl.fcen.uba.ar/Universidad públicaNo correspondehttps://digital.bl.fcen.uba.ar/cgi-bin/oaiserver.cgiana@bl.fcen.uba.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:18962025-10-23 11:18:32.714Biblioteca Digital (UBA-FCEN) - Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturalesfalse |
dc.title.none.fl_str_mv |
Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence? |
title |
Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence? |
spellingShingle |
Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence? Pérez-Cuesta, L.M. animal experiment article aversion conditioning controlled study crab exposure learning long term memory male memory consolidation nonhuman priority journal reinforcement stimulus symbiosis training working memory Animals Behavior, Animal Brachyura Conditioning, Classical Cycloheximide Extinction, Psychological Male Memory Protein Synthesis Inhibitors Time Factors |
title_short |
Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence? |
title_full |
Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence? |
title_fullStr |
Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence? |
title_full_unstemmed |
Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence? |
title_sort |
Memory reconsolidation and extinction in the crab: Mutual exclusion or coexistence? |
dc.creator.none.fl_str_mv |
Pérez-Cuesta, L.M. Maldonado, H. |
author |
Pérez-Cuesta, L.M. |
author_facet |
Pérez-Cuesta, L.M. Maldonado, H. |
author_role |
author |
author2 |
Maldonado, H. |
author2_role |
author |
dc.subject.none.fl_str_mv |
animal experiment article aversion conditioning controlled study crab exposure learning long term memory male memory consolidation nonhuman priority journal reinforcement stimulus symbiosis training working memory Animals Behavior, Animal Brachyura Conditioning, Classical Cycloheximide Extinction, Psychological Male Memory Protein Synthesis Inhibitors Time Factors |
topic |
animal experiment article aversion conditioning controlled study crab exposure learning long term memory male memory consolidation nonhuman priority journal reinforcement stimulus symbiosis training working memory Animals Behavior, Animal Brachyura Conditioning, Classical Cycloheximide Extinction, Psychological Male Memory Protein Synthesis Inhibitors Time Factors |
dc.description.none.fl_txt_mv |
A conditioned stimulus (CS) exposure has the ability to induce two qualitatively different mnesic processes: memory reconsolidation and memory extinction. Previous work from our laboratory has shown that upon a single CS presentation the triggering of one or the other process depends on CS duration (short CS exposure triggers reconsolidation, whereas a long CS exposure triggers extinction), both being mutually exclusive processes. Here we show that either process is triggered only after CS offset, ruling out an interaction as the mechanism of this mutual exclusion. Also, we show here for the first time that reconsolidation and extinction can occur simultaneously without interfering with each other if they are serially triggered by respective short and long CS exposures. Thus, we conclude that (1) one single CS presentation triggers one single process, after CS offset, and (2) whether memory reconsolidation and extinction mutually exclude each other or whether they coexist depends only on whether they are triggered by single or multiple CS presentations. © 2009 Cold Spring Harbor Laboratory Press. Fil:Pérez-Cuesta, L.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. |
description |
A conditioned stimulus (CS) exposure has the ability to induce two qualitatively different mnesic processes: memory reconsolidation and memory extinction. Previous work from our laboratory has shown that upon a single CS presentation the triggering of one or the other process depends on CS duration (short CS exposure triggers reconsolidation, whereas a long CS exposure triggers extinction), both being mutually exclusive processes. Here we show that either process is triggered only after CS offset, ruling out an interaction as the mechanism of this mutual exclusion. Also, we show here for the first time that reconsolidation and extinction can occur simultaneously without interfering with each other if they are serially triggered by respective short and long CS exposures. Thus, we conclude that (1) one single CS presentation triggers one single process, after CS offset, and (2) whether memory reconsolidation and extinction mutually exclude each other or whether they coexist depends only on whether they are triggered by single or multiple CS presentations. © 2009 Cold Spring Harbor Laboratory Press. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/20.500.12110/paper_10720502_v16_n11_p714_PerezCuesta |
url |
http://hdl.handle.net/20.500.12110/paper_10720502_v16_n11_p714_PerezCuesta |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/2.5/ar |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Learn. Mem. 2009;16(11):714-721 reponame:Biblioteca Digital (UBA-FCEN) instname:Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales instacron:UBA-FCEN |
reponame_str |
Biblioteca Digital (UBA-FCEN) |
collection |
Biblioteca Digital (UBA-FCEN) |
instname_str |
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales |
instacron_str |
UBA-FCEN |
institution |
UBA-FCEN |
repository.name.fl_str_mv |
Biblioteca Digital (UBA-FCEN) - Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales |
repository.mail.fl_str_mv |
ana@bl.fcen.uba.ar |
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1846784881050255360 |
score |
12.982451 |