Publication Date: 2019.
Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments.
Instituto de Patobiología
Author affiliation: Jalovecka, Marie. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa. University of South Bohemia. Faculty of Science; República Checa
Author affiliation: Sojka, Daniel. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa
Author affiliation: Ascencio, Mariano E. INTA. Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Author affiliation: Schnittger, Leonhard. INTA. Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Repository: INTA Digital (INTA). Instituto Nacional de Tecnología Agropecuaria