Development of a construct-based risk assessment framework for genetic engineered crops

Authors
Becker, M.P.; Boari, P.; Burachik, Moisés; Cuadrado, V.; Junco, Mariano; Lede, S.; Lema, Martín; Lewi, Dalia Marcela; Maggi, Andrés; Meoniz,Ignacio Alberto; Noe, G.; Roca, Cecilia; Robredo, Claudio Gabriel; Rubinstein, Clara; Vicien, Carmen; Whelan, Agustina
Publication Year
2016
Language
English
Format
article
Status
Versión aceptada para publicación
Description
Experience gained in the risk assessment (RA) of genetically engineered (GE) crops since their first experimental introductions in the early nineties, has increased the level of familiarity with these breeding methodologies and has motivated several agencies and expert groups worldwide to revisit the scientific criteria underlying the RA process. Along these lines, the need to engage in a scientific discussion for the case of GE crops transformed with similar constructs was recently identified in Argentina. In response to this need, the Argentine branch of the International Life Sciences Institute (ILSI Argentina) convened a tripartite working group to discuss a science-based evaluation approach for transformation events developed with genetic constructs which are identical or similar to those used in previously evaluated or approved GE crops. This discussion considered new transformation events within the same or different species and covered both environmental and food safety aspects. A construct similarity concept was defined, considering the biological function of the introduced genes. Factors like environmental and dietary exposure, familiarity with both the crop and the trait as well as the crop biology, were identified as key to inform a construct-based RA process.
Inst. de Genética "Ewald A. Favret"- IGEAF
Fil: Becker, M.P. Bayer SA,; Argentina
Fil: Boari, P. Ministerio de Agroindustria. Secretaría de Valor Agregado. Dirección de Biotecnología; Argentina
Fil: Burachik, Moisés. Instituto de Agrobiotecnologia Rosario; Argentina
Fil: Cuadrado, V. Monsanto Argentina; Argentina
Fil: Junco, Mariano. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Coordinación de Biotecnología y Productos Industrializados; Argentina
Fil: Lede, S. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Lema, Martín. Ministerio de Agroindustria. Secretaría de Valor Agregado. Dirección de Biotecnología; Argentina
Fil: Lewi, Dalia Marcela. INTA. Instituto de Genética "Ewald A. Favret"; Argentina
Fil: Maggi, Andrés. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección de Calidad Agroalimentaria; Argentina
Fil: Meoniz, Ignacio Alberto. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Análisis de Riesgo de Organismos Genéricamente Modificados; Argentina
Fil: Noe, G. Syngenta Agro; Argentina
Fil: Roca, Cecilia. Dow Agroscience SA; Argentina
Fil: Robredo, Claudio Gabriel. Chacra Experimental Agrícola Santa Rosa; Argentina
Fil: Rubinstein, Clara. Monsanto Argentina; Argantina. Instituto Internacional de Ciencias de la Vida; Argentina
Fil: Vicien, Carmen. Universidad de Buenos Aires; Argentina. Cámara de Exportadores de la República Argentina; Argentina
Fil: Whelan, Agustina. Ministerio de Agroindustria. Secretaría de Valor Agregado. Dirección de Biotecnología; Argentina
Source
Transgenic research 25 (5) : 597–607. (October 2016)
Subject
Genética
Evaluación de Riesgos
Ingeniería Genética
Genetics
Risk Assessment
Genetic Engineering
Access level
Restricted access
License
Repository
INTA Digital (INTA)
Institution
Instituto Nacional de Tecnología Agropecuaria
OAI Identifier
oai:localhost:20.500.12123/1103