Genomic characterization of a rotavirus G8P[1] detected in a child with diarrhea reveal direct animal-to-human transmission

Authors
Martinez, Magaly; Phan, Tung Gia; Galeano, Maria Eugenia; Russomando, Graciela Mabel; Parreño, Gladys Viviana; Delawart, Eric; Parra, Gabriel
Publication Year
2014
Language
English
Format
article
Status
Published version
Description
Group A rotavirus is a major cause of severe gastroenteritis in children and young animals. During a retrospective analysis of samples collected from Paraguayan children under 5 years old with diarrhea, and previously negative for rotavirus and norovirus, we detected the presence of bovine rotavirus sequences by viral metagenomics. Nucleic acid was extracted direct from stool sample and determined to be G8P[1]. The genomic analyzes revealed that the strain presents an Artiodactyl-like genome (G8-P[1]-I2-R2-C2-M1-Ax-N2-T6-E12-H3) suggesting a direct animal-to-human transmission.
Fil: Martinez, Magaly. Universidad Nacional de Asunción; Paraguay
Fil: Phan, Tung Gia. Blood Systems Research Institute. San Francisco; Estados Unidos
Fil: Galeano, Maria Eugenia. Universidad Nacional de Asunción; Paraguay
Fil: Russomando, Graciela Mabel. Universidad Nacional de Asunción; Paraguay
Fil: Parreño, Gladys Viviana. Instituto Nacional de Tecnología Agropecuaria; Argentina
Fil: Delawart, Eric. Blood Systems Research Institute. San Francisco; Estados Unidos
Fil: Parra, Gabriel. Universidad Nacional de Asunción; Paraguay
Subject
Rotavirus
Interspecies transmission
Bovine-like rotavirus
G8P[1]
Salud Ocupacional
Ciencias de la Salud
CIENCIAS MÉDICAS Y DE LA SALUD
Access level
Restricted access
License
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repository
CONICET Digital (CONICET)
Institution
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identifier
oai:ri.conicet.gov.ar:11336/36427