Inhibition of immediate-type allergic reaction by Minthostachys verticillata (Griseb.) epling essential oil

Authors
Cariddi, Laura Noelia; Panero, Adriana; Demo, Mirta Susana; Sabini, Liliana Ines; Maldonado, Ana Maria; Grosso, Margarita; Zygadlo, Julio Alberto
Publication Year
2007
Language
English
Format
article
Status
Published version
Description
An oil of Minthostachys verticillata (Griseb.) Epling was analyzed by GC. The main constituents identified were pulegone (63.0%) and menthone (16.4%). It was found that the oil inhibited β-hexosaminidase release from basophils. Forty-two percent of the cells present in lymphocyte cultures stimulated by the oil were CD8(+) T cells and showed higher IFN-γ levels than non-stimulated cultures (p < 0.05). According to these results, the oil was considered to be a Th1 deviation inducer, inhibiting the immediate-type allergic reaction. © 2007, Taylor & Francis Group, LLC. All rights reserved.
Fil: Cariddi, Laura Noelia. Universidad Nacional de Río Cuarto; Argentina
Fil: Panero, Adriana. Universidad Nacional de Río Cuarto; Argentina
Fil: Demo, Mirta Susana. Universidad Nacional de Río Cuarto; Argentina
Fil: Sabini, Liliana Ines. Universidad Nacional de Río Cuarto; Argentina
Fil: Maldonado, Ana Maria. Universidad Nacional de Río Cuarto; Argentina
Fil: Grosso, Margarita. Universidad Nacional de Río Cuarto; Argentina
Fil: Zygadlo, Julio Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Subject
ANTI-ALLERGIC EFFECT
ESSENTIAL OIL COMPOSITION
LABIATAE
MENTHONE
MINTHOSTACHYS VERTICILLATA
PULEGONE
Inmunología
Medicina Básica
CIENCIAS MÉDICAS Y DE LA SALUD
Access level
Restricted access
License
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repository
CONICET Digital (CONICET)
Institution
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identifier
oai:ri.conicet.gov.ar:11336/37385