First genotoxicity study of Paraná River water from Argentina using cells from the clam Corbicula fluminea (veneroida corbiculidae) and Chinese hamster (Cricetulus griseus Rodentia...

Authors
Caffetti, Jacqueline Diana; Mantovani, Mário S.; Pastori, María Cristina; Fernocchio, Alberto S.
Publication Year
2008
Language
English
Format
article
Status
Published version
Description
High concentrations of xenobiotics from urban and industrial wastes have contributed to the contamination of many aquatic environments. We used the comet assay to evaluate the genotoxic potential of water collected from the River Paraná, which receives a great deal of waste, at three points (Puerto Piray, Eldorado and Montecarlo) in the Misiones Province of Argentina. The in vivo comet assay used 40 freshwater clams (Corbicula fluminea) while the in vitro comet assay used Chinese hamster (Cricetulus griseus) K1 cell (CHO-K1) cultures with the mutagen ethyl methanesulfonate (EMS) as the positive control and phosphate buffered saline (PBS) as the negative control. Both assays showed statistically significant differences between the three sampling sites in relation to the negative control, the results of this preliminary study indicating that at these three sites water from the Paraná River presents genotoxic potential. Copyright © 2008, Sociedade Brasileira de Genética.
Fil: Caffetti, Jacqueline Diana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Posadas | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Posadas; Argentina
Fil: Mantovani, Mário S.. Universidade Estadual de Londrina; Brasil
Fil: Pastori, María Cristina. Universidad Nacional de Misiones; Argentina
Fil: Fernocchio, Alberto S.. Universidad Nacional de Misiones; Argentina
Subject
BIOMONITORING
CHO-K1 CELLS
COMET ASSAY
CORBICULA FLUMINEA
GENOTOXICITY
PARANA RIVER
Bioquímica y Biología Molecular
Ciencias Biológicas
CIENCIAS NATURALES Y EXACTAS
Access level
Open access
License
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repository
CONICET Digital (CONICET)
Institution
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identifier
oai:ri.conicet.gov.ar:11336/60204