First study about the development of adult Echinococcus canadensis G6 genotype of goat origin in experimentally infected dogs

Authors
Soriano, Silvia Viviana; Debiaggi, Maria Florencia; Pierangeli, Nora Beatriz; Pianciola, Luis Alfredo; Bergagna, Héctor Fabián Jesús; Lazzarini, Lorena Evelina; Mazzeo, Melina; Basualdo Farjat, Juan Angel
Publication Year
2016
Language
English
Format
article
Status
Published version
Description
Echinococcus granulosus sensu lato (E. granulosus sl) must be considered as a species complex, comprising Echinococcus granulosus sensu stricto (E. granulosus ss, genotypes G1-G3), Echinococcus equinus (G4), Echinococcus ortleppi (G5) and Echinococcus canadensis (G6-G10) although the species status of E. canadensis is still controversial. These genotypes closely match the intermediate hosts associated strains described in earlier times among which E. canadensis G6 corresponds to the camel strain. As there are no studies concerning the development of adult stages of the G6 genotype from non-camel origin, the aims of the present study were: to characterize for the first time the development of E. canadensis G6 in dogs experimentally infected with protoscoleces derived from goats, to describe the resultant adult morphology, to evaluate the growth of their rostellar hooks from larval to adult stages and to determine the prepatent period of the strobilar stage of E. canadensis G6 derived from goats. The development of the strobilar stage of E. canadensis G6 genotype of goat origin was examined by studying the growth (variation of the total worm length) and segmentation in experimentally infected dogs at 14, 25, 35 and 56 days post infection. A morphological characterization of 35-day-old worms as well as of larval and adult rostellar hooks was also carried out by conventional optical microscopic observations and/or by scanning electron microscopy. The prepatent period of the strobilar stage was assessed by microscopic examination of faeces from 2 infected dogs. Our results were compared with published data from the camel and other strains. The roles of the host, genotype and species in morphological and developmental features as well as the taxonomic position of E. canadensis G6 were discussed. The prepatent period of E. canadensis G6 genotype of goat origin was determined as at least, 41 days. The obtained results contribute to increase the knowledge about the biology and genetics of E. granulosus sl complex and are also of practical usefulness for the design of disease control strategies.
Fil: Soriano, Silvia Viviana. Universidad Nacional del Comahue. Facultad de Medicina; Argentina
Fil: Debiaggi, Maria Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina. Universidad Nacional del Comahue. Facultad de Medicina; Argentina
Fil: Pierangeli, Nora Beatriz. Universidad Nacional del Comahue. Facultad de Medicina; Argentina
Fil: Pianciola, Luis Alfredo. Provincia de Neuquén. Subsecretaría de Salud; Argentina
Fil: Bergagna, Héctor Fabián Jesús. Universidad Nacional del Comahue. Facultad de Medicina; Argentina
Fil: Lazzarini, Lorena Evelina. Universidad Nacional del Comahue. Facultad de Medicina; Argentina
Fil: Mazzeo, Melina. Provincia de Neuquén. Subsecretaría de Salud; Argentina
Fil: Basualdo Farjat, Juan Angel. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; Argentina
Subject
ECHINOCOCCUS CANADENSIS G6 GENOTYPE
ECHINOCOCCUS GRANULOSUS SENSU LATO
HOOK MORPHOMETRY
PARASITE DEVELOPMENT
PREPATENT PERIOD
Salud Ocupacional
Ciencias de la Salud
CIENCIAS MÉDICAS Y DE LA SALUD
Access level
Restricted access
License
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repository
CONICET Digital (CONICET)
Institution
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identifier
oai:ri.conicet.gov.ar:11336/79044