Extrachromosomal genetic elements in Micrococcus

Authors
Dib, Julian Rafael; Liebl, Wolfgang; Wagenknecht, M.; Farias, Maria Eugenia; Meinhardt, Friedhelm
Publication Year
2012
Language
English
Format
article
Status
Published version
Description
Micrococci are Gram-positive G+C-rich, nonmotile, nonspore-forming actinomycetous bacteria. Micrococcus comprises ten members, with Micrococcus luteus being the type species. Representatives of the genus play important roles in the biodegradation of xenobiotics, bioremediation processes, production of biotechnologically important enzymes or bioactive compounds, as test strains in biological assays for lysozyme and antibiotics, and as infective agents in immunocompromised humans. The first description of plasmids dates back approximately 28 years, when several extrachromosomal elements ranging in size from 1.5 to 30.2 kb were found in Micrococcus luteus. Up to the present, a number of circular plasmids conferring antibiotic resistance, the ability to degrade aromatic compounds, and osmotolerance are known, as well as cryptic elements with unidentified functions. Here, we review the Micrococcus extrachromosomal traits reported thus far including phages and the only quite recently described large linear extrachromosomal genetic elements, termed linear plasmids, which range in size from 75 kb (pJD12) to 110 kb (pLMA1) and which confer putative advantageous capabilities, such as antibiotic or heavy metal resistances (inferred from sequence analyses and curing experiments). The role of the extrachromosomal elements for the frequently proven ecological and biotechnological versatility of the genus will be addressed as well as their potential for the development and use as genetic tools.
Fil: Dib, Julian Rafael. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos (i); Argentina; Westfälische Wilhelms-Universität Münster. Institut für Molekulare Mikrobiologie und Biotechnologie; Alemania,;
Fil: Liebl, Wolfgang. Technische Universität München. Lehrstuhl für Mikrobiologie; Alemania;
Fil: Wagenknecht, M.. Westfälische Wilhelms-Universität Münster. Institut für Molekulare Mikrobiologie und Biotechnologie; Alemania,;
Fil: Farias, Maria Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos (i); Argentina;
Fil: Meinhardt, Friedhelm. Westfälische Wilhelms-Universität Münster. Institut für Molekulare Mikrobiologie und Biotechnologie; Alemania,;
Subject
Plasmids
Micrococcus
Andean lakes
UV radiation
Extrachromosomal elements
Biología Celular, Microbiología
Ciencias Biológicas
CIENCIAS NATURALES Y EXACTAS
Biotecnología relacionada con la Salud
Biotecnología de la Salud
CIENCIAS MÉDICAS Y DE LA SALUD
Access level
Restricted access
License
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repository
CONICET Digital (CONICET)
Institution
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identifier
oai:ri.conicet.gov.ar:11336/1705